Article Type





ORTHO An observational study evaluating the efficacy of microfragmented adipose tissue in the treatment of osteoarthritis Fan, Regenerative Medicine, Published Online: 21 Dec 2022 2022 Knee/Shoulder
BASIC SCIENCE Surgical implantation of human adipose derived stem cells attenuates experimentally
induced hepatic  brosis in rats
Nomura et al. Molecular Medicine (2022) 28:143 2022 Hepatic
REVIEW Regulatory and Ethical Aspects of Orthobiologic Therapies Murray, Biologics Association, The Orthopaedic Journal of Sports Medicine, 10(11), 23259671221101626 DOI: 10.1177/23259671221101626 2022 Regulatory
ORTHO Is intra‐articular injection of autologous micro‐fragmented adipose tissue e ective in hip osteoarthritis? A three year follow‐up Natali, Zorzi, et al., International Orthopaedics, October 2022, 2022 Hip Standalone
BASIC SCIENCE Micro-fragmented adipose tissue regulated the biological functions of
osteoarthritis synoviocytes by upregulating MiR-92a-3p expression
Z. Shi et al., Tissue and Cell 74 (2022) 101716 2022 Synoviocytes
GEN SURG Regenerative and Endoscopic Treatment of Complex Recurrent Fistula in Ano:
When Technology Supports Clinical Treatment
Monti, Int J Regenr Med doi: 10.31487/j.RGM.2022.02.03 Volume 5(2): 2-7 2022 Fistula
ORTHO Platelet-Rich Plasma Versus Microfragmented Adipose Tissue for Knee Osteoarthritis Baria et al., The Orthopaedic Journal of Sports Medicine, 10(9), 23259671221120678, 2022 2022 Knee Standalone
GEN SURG Stemming the Leak: A Novel Treatment for Gastro‐Bronchial Fistula F. M. Mongardini, et al., Digestive Diseases and Sciences, 2022 2022 Fistula
REVIEW Microfractured Adipose Tissue Graft (Lipogems) and Regenerative Surgery Tremolada C (2022) Microfractured Adipose Tissue Graft (lipogems) and Regenerative Surgery. J Orthop Res Ther 7: 1210 DOI: 10.29011/2575-8241.001210 2022 Overview
GEN SURG Echo-Assisted Intersphincteric Autologous Microfragmented Adipose Tissue Injection to Control Fecal Incontinence in Children M. Lima, G. Ruggeri (eds.), Ano-Rectal Endosonography and Manometry in Paediatrics, 2022 Fecal Incontinence
ORTHO Age and synovitis affect the results of the treatment of knee osteoarthritis with Microfragmented Autologous Fat Tissue Ferracini et. al,  Knee Surgery, Sports Traumatology, Arthroscopy, 20 August 2022, 2022 Knee Adjunct
ORTHO Micro‐fragmented adipose tissue (mFAT) associated with arthroscopic debridement provides functional improvement in knee osteoarthritis: a randomized controlled trial Ulivi, de Girolamo, et al; Knee Surgery, Sports Traumatology, Arthroscopy 2022 Knee Adjunct
ORTHO Autologous microfragmented adipose tissue and leukocyte-poor platelet-rich plasma combined with hyaluronic acid show comparable clinical outcomes for symptomatic early knee osteoarthritis
over a two-year follow-up period: a prospective randomized clinical trial
Gobbi, Dallo, et al, European Journal of Orthopaedic Surgery & Traumatology, 2022 Knee Standalone
ORTHO Microfragmented Adipose Tissue Versus Platelet-Rich Plasma for the Treatment of Knee Osteoarthritis: A Prospective Randomized Controlled Trial at 2-Year Follow-up Zaffagnini, Filardo, Kon, et al, The American Journal of Sports Medicine
1–12. DOI: 10.1177/03635465221115821
2022 Knee Standalone
ORTHO Intra-Articular Injections of Autologous Adipose Tissue or Platelet-Rich Plasma Comparably Improve Clinical and Functional Outcomes in Patients with Knee Osteoarthritis Kaszynski et al., Biomedicines 2022, 10, 684. 2022 Knee Standalone
ORTHO Arthroscopic Rotator Cuff Repair Augmentation With Autologous Microfragmented Lipoaspirate Tissue Randelli et al, American Journal of Sports Medicine, 2022 2022 Shoulder Adjunct
ORTHO Autologous Microfragmented Adipose Tissue for the Treatment of Knee Osteoarthritis: Real World Data at Two Years Follow Up Screpis, D.; Zorzi, C. Med. 2022, 11, 1268. 2022 Knee Standalone
ORTHO Comparison of the Effect of MFAT and MFAT + PRP on Treatment of Hip Osteoarthritis: An Observational, Intention-to-Treat Study at One Year Heidari, N, et al., J.Clin.Med.2022,11,1056. https:// 2022 Hip
ORTHO Intraarticular injection of microfragmented adipose tissue plus arthroscopy in isolated primary patellofemoral osteoarthritis is clinically effective and not afected by age, BMI, or stage of osteoarthritis Panni, Vasso et al. Journal of Orthopaedics and Traumatology (2022) 23:7
2022 Knee Adjunct
BASIC SCIENCE Comparison of Clinically Relevant Adipose Preparations on Articular
Chondrocyte Phenotype in a Novel In Vitro Co-Culture Model
Kokai, Rubin, Onishi, et al, Stem Cells and Development, 2022 2022 Cartilage
BASIC SCIENCE Lipoaspirate Shows In Vitro Potential for Wound Healing  Ceresa, C.; Bosetti, M., et al. Pharmaceutics 2022,14,447. 10.3390/pharmaceutics14020447 2022 Wound Healing
BASIC SCIENCE Long-term in vivo survival of 3D-bioprinted human lipoaspirate-derived adipose
tissue: proteomic signature and cellular content
Karin Säljö & Lars Kölby (2022), Adipocyte, 11:1, 34-46, DOI: 10.1080/21623945.2021.2014179 2022 Cells
GEN SURG Autologous micro-fragmented fat injection results in cases of complex perianal fistula in patients with Crohn’s disease SEGURA et al, Chirurgia 2022 February;35(1):51-4, EDIZIONI MINERVA MEDICA 2021 Fistula
ORTHO Adipose-Derived Stem Cells for Hip Osteoarthritis: A Promising Case Series Coco, V., Russo, A., et al., Annals of Case Reports & Reviews (2021) ACRR-292, doi: 10.39127/2574-5747/ACRR:1000292 2021 Hip
ORTHO Health-related quality of life outcomes and hospitalization length of stay after micro-fragmented autologous adipose tissue injection in minor amputations for diabetic foot ulceration (MiFraaDif trial): results from a randomized controlled single-center clinical trial GENNAI et al., International Angiology 2021; Vol. 40 DOI: 10.23736/S0392 9590.21.04570-3 2021 Diabetic Foot Ulcers
ORTHO A Prospective Study Comparing Leukocyte-Poor Platelet-Rich Plasma Combined with Hyaluronic Acid and Autologous Microfragmented Adipose Tissue in Patients with Early Knee Osteoarthritis Dallo, Gobbi, et. al., STEM CELLS AND DEVELOPMENT Volume 30, Number 13, 2021 2021 Knee Standalone
ORTHO The use of intra‐articular injection of autologous micro‐fragmented adipose tissue as pain treatment for ankle osteoarthritis: a prospective not randomized clinical study Natali, Zorzi, et al., International Orthopaedics, June 2021, 2021 Foot & Ankle
ORTHO Microfragmented Adipose Tissue Injection (MFAT) May Be a Solution to the Rationing of Total Knee Replacement: A Prospective, Gender-Bias Mitigated, Reproducible Analysis at Two Years Heidari, Wilson, et al., Hindawi
, Stem Cells International, Volume 2021, Article ID 9921015,
2021 Knee Standalone
ORTHO Autologous Micro-Fragmented Adipose Tissue (MFAT) to Treat Symptomatic Knee Osteoarthritis: Early Outcomes of a Consecutive Case Series Verdonk et al, J. Clin. Med. 2021, 10, 2231. 2021 Knee Standalone
ORTHO A pilot study to evaluate micro-fragmented adipose tissue injection under ultrasound guidance for the treatment of refractory rotator cuff disease in wheelchair users with spinal cord injury Nathan Hogaboom, Gerard Malanga, Chris Cherian & Trevor Dyson-Hudson (2021), The Journal of Spinal Cord Medicine, DOI: 10.1080/10790268.2021.1903140 2021 Shoulder
ORTHO Temporomandibular Joint Arthrocentesis and Microfragmented Adipose Tissue Injection for the Treatment of Internal Derangement and Osteoarthritis: A Randomized Clinical Trial Sembronio, Tremolada, et al. Journal of Oral and Maxillofacial Surgery. 2021. 2021 TMJ
ORTHO Treatment of knee osteoarthritis by intra-articular injection of concentrated autologous adipose tissue: a twenty four month follow-up study Ferracini, et al., International Orthopaedics (2021) 45:627–633 2021 Knee
ORTHO Two-year clinical outcomes of autologous microfragmented adipose tissue in elderly patients with knee osteoarthritis: a multi-centric, international study Gobbi, Ignacio, Rogers, Striano, Mautner, Bowers, Rozak, Bilbool, Murrell, International Orthopaedics, March 2021 2021 Knee
ORTHO Gender-Specific Response in Pain and Function to Biologic Treatment of Knee Osteoarthritis: A Gender-Bias-Mitigated, Observational, Intention-to-Treat Study at Two Years Wilson A. , Stem Cells International, Volume 2021, Article ID 6648437 2021 Knee
ORTHO Micro‐fragmentation is a valid alternative to cell expansion Filardo, Tschon, Kon, et al; Knee Surgery, Sports Traumatology, Arthroscopy; Jan. 2021 2021 Knee
REVIEW Mesenchymal stem cells in orthopedics – a current perspective Primorac, Engineering Power, Vol. 16(1) 2021 2021 Knee Standalone
VET Case Report: Microfragmented Adipose Tissue Drug Delivery in Canine Mesothelioma: A Case Report on Safety, Feasibility, and Clinical Findings ZEIRA, O., et al. Frontiers in Veterinary Science, 2021 2021 Canine
BASIC SCIENCE Microfragmented adipose tissue is associated with improved ex vivo performance linked to HOXB7 and b-FGF expression Casari, et al., Stem Cell Res Ther (2021) 12:481 2021 Cells
BASIC SCIENCE Characterisation of Novel Angiogenic and Potent Anti-Inflammatory Effects of Micro-Fragmented Adipose Tissue Guo,B.; Sawkulycz,X.; Heidari, N.; Rogers, R.; Liu, D.; Slevin, M. Int. J. Mol. Sci. 2021, 22, 3271. 2021 Cells
GEN SURG Treatment of fistula-in-ano: Outcome comparison between traditional surgery and novel approaches. A retrospective cohort study in a single center Fabbri N, Ascanelli S, D’urbano F, Resta G, Cavallesco G, Carcoforo P, J Surg Med. 2020;4(7):582-586. 2020 Fistula
GEN SURG Endoscopic repair of a vesicouterine fistula with the injection of microfragmented autologous adipose tissue (Lipogems®) Spinelli, Montanari, et al., Turk J Urol 30 July 2020. 10.5152/tud.2020.20170 2020 Fistula
GEN SURG Endoscopic repair of a vesicouterine fistula with the injection of microfragmented autologous adipose tissue (Lipogems®) Spinelli, Montanari, et al., Turk J Urol 30 July 2020. 10.5152/tud.2020.20170 2020 Fistula
GYN A new treatment of genito-urinary post-menopausal atrophy with autologous micro-fragmented fat tissue: a thirty-six months follow up case series G. CASAROTTI, C. TREMOLADA; European Review for Medical and Pharmacological Sciences; 2020; 24: 7420-7426 2020 Vaginal Atrophy
GYN Safety and Feasibility of Autologous Micro-Fragmented Adipose Tissue Injections for the Treatment of Vaginal Atrophy, Vulvovaginal Dystrophy, and Stress Urinary Incontinence: An Observational Case Series Stark, Razzaque, Yoon, Aref-Adib, Banwell, Beski, EMJ Urol. 2020;8[1]:29-37. 2020 Vaginal Atrophy
ORTHO Open-wedge high tibial osteotomy associated with lipogems® intra-articular injection for the treatment of varus knee osteoarthritis – retrospective study ZORZI, Acta Biomed 2020; Vol. 91, S. 14: e2020022 2020 Knee
ORTHO Clinical use of autologous micro-fragmented fat progressively restores pain and function in shoulder osteoarthritis Vinet-Jones & Kevin F Darr; Regen.Med., 10.2217/rme-2020-0069 2020 Shoulder
ORTHO Clinical evaluation of micro-fragmented adipose tissue as a treatment option for patients with meniscus tears with osteoarthritis: a prospective pilot study Malanga, Chirichella, Hogaboom, Capella; International Orthopaedics; October 2020; 2020 Knee Standalone
ORTHO Patient-Centered Outcomes of Microfragmented Adipose Tissue Treatments of Knee Osteoarthritis: An Observational, Intention-to-Treat Study at Twelve Months HEIDARI, WILSON, et al. Hindawi Stem Cells International, Volume 2020, Article ID 8881405, 8 pages, 2020 2020 Knee Standalone
ORTHO Arthroscopic Debridement and Autologous Micronized Adipose Tissue Injection in the Treatment of Advanced-Stage Posttraumatic Osteoarthritis of the Ankle SHIMOZONO, DANKERT, KENNEDY; Cartilage, 2020; DttOpsI://1d0o.i1.o1r7g/71/01.1914776/1093457260395426039646436 2020 Foot & Ankle
ORTHO Chemical Profile and Clincal Efficacy of Adipose-Derived Proceedings Mesenchymal Stromal Cell Therapy in the Treatment of Knee Osteoarthritis HABER, J., HOGABOOM, N., MALANGA, G.; Biologic Orthopedic Journal, Vol 2(1):e13–e24; June 23, 2020 2020 Knee Standalone
REVIEW Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Primorac, Hudetz, Boric ́; Genes 2020, 11, 854; doi:10.3390/genes11080854 2020 Pathogenesis
REVIEW Chemical Profile and Clinical Efficacy of Micro-Fragmented Adipose Tissue in the Treatment of Knee Osteoarthritis HABER, HOGABOOM, MALANGA; Bio Ortho J Vol 2(1):e13–e24; June 23, 2020 2020 Basic Science
TECHNIQUE Autologous Adipose Orthobiologic Cell Therapy Harvest Technique Halbrecht , Graivier; Operative Techniques in Sports Medicine 2020 Technique
BASIC SCIENCE Autologous microfragmented adipose tissue reduces inflammatory and catabolic markers in supraspinatus tendon cells derived Viganò, M., Randelli, DeGirolamo, Lugano, G., Perucca Orfei, C. et al. A; International Orthopaedics (SICOT) (2020). 2020 Tendon
BASIC SCIENCE Successful engraftment, vascularization, and In vivo survival of 3D-bio- printed human lipoaspirate-derived adipose tissue SALJO, K., et al. Bioprinting 17 (2020) e00065 2020 Scaffold
BASIC SCIENCE Micro Fragmented Adipose Tissue Promotes the Matrix Synthesis Function of Nucleus Pulposus Cells and Regenerates Degenerated Intervertebral Disc in a Pig Model ZHOU, X., Cell Transplantation, Vol. 29(1) 1–14, 2020 2020 DDD
ORTHO Functional Outcomes Following Microfragmented Adipose Tissue Versus Bone Marrow Aspirate Concentrate Injections for Symptomatic Knee Osteoarthritis Mautner, Bowers, Easley et al., STEM CELLS TRANSLATIONAL MEDICINE 2019;8:1149–1156 2019 Knee Standalone
GEN SURG Microfragmented Adipose Tissue and Blood Plasma-Based Hydrogels for Treatment of Combat-Associated Burn Injuries” Shanmugasundaram Natesan, PhD, US Army Institute of Surgical Research, Ft. Sam Houston 2019 Burn/Wound
GEN SURG Refractory Complex Crohn’s Perianal Fistulas: A Role for Autologous Microfragmented Adipose Tissue Injection LAURETI, S., et al. Inflammatory Bowel Diseases,2019. 2019 Fistula
GEN SURG Rectal advancement  ap plus adipose lipo lling (RAFAL) for the treatment of rectourethral  stulas after radical prostatectomy ZUIN, M. et al. Techniques in Coloproctology, 2019  2019 Prostatectomy
GYN Evaluation of fat grafting technique using autologous micro-fragmented adipose tissue (Lipogems®) in female patients suffering from stress urinary incontinence SANTOS-CORTES, Int Clin Med, 2019 2019 Urinary Incontinence
ORTHO Mesenchymal Stem Cells injection in hip osteoarthritis: preliminary results DALL’OCA, C., et al.  Acta Bio Medica Atenei Parmensis, 2019; 90.1-S: 75-80. 2019 Hip
ORTHO A 24-Month Follow-Up Study of the Effect of Intra-Articular Injection of Autologous Microfragmented Fat Tissue on Proteoglycan Synthesis in Patients with Knee Osteoarthritis BORIC ́, HUDETZ, Genes 2019, 10, 1051 2019 Knee Standalone
ORTHO Treatment of osteoarthritis with autologous and microfragmented adipose tissue BARFOD, BLløND, Danish Medical Journal 2019;66(10):A5565 2019 Knee Standalone
ORTHO Micro-fragmented stromal-vascular fraction plus microfractures provides better clinical results than microfractures alone in symptomatic focal chondral lesions of the knee BISICCHIA, et al. European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2019 2019 Knee Adjunct
ORTHO Early results of intra-articular micro-fragmented lipoaspirate treatment in patients with late stages knee osteoarthritis: a prospective study. HUDETZ, D., BORIC, I. et al., Croat Med J. 2019 Jun 13;60(3):227-236 2019 Knee Standalone
ORTHO Autologous micro-fragmented adipose tissue for the treatment of diabetic foot minor amputations: a randomized controlled single-center clinical trial (MiFrAADiF)  LONARDI R., LEONE N., et al. Stem Cell Research & Therapy (2019) 10:223 2019 Foot/ankle
ORTHO Micro-fragmented Adipose Tissue Transplantation (MATT) for the treatment of acetabular delamination. A two years follow up comparison study with microfractures IVONE, A. FIORUZZI, E. JANNELLI, et al., Acta Biomed 2019; Vol. 90, Supplement 12: 69-75 2019 Hip
REVIEW Mesenchymal Stromal Cells and Micro Fragmented Adipose Tissue: New Horizons of Effectiveness of Lipogems TREMOLADA C, et al., J Stem Cell Res Dev 2019, 5: 017 2019  
BASIC SCIENCE Autologous Micro-Fragmented Adipose Tissue as Stem Cell-Based Natural  Scaffold for Cartilage Defect Repair Xu, Dai, et al., Cell Transplantation 2019, Vol. 28(12) 1709–1720 2019 Animal Cartilage
BASIC SCIENCE Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy ALESSANDRI, g., et al. Journal of Controlled Release, 2019. 2019 Scaffold
BASIC SCIENCE Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue NAVA, S., et al. Stem Cells International 2019 2019 Inflammation
BASIC SCIENCE Regenerative Features of Adipose Tissue for Osteoarthritis Treatment in a Rabbit Model: Enzymatic Digestion Versus Mechanical Disruption FILARDO, KON, GRIGOLO, et al. Int. J. Molecular Sciences. 2019, 20, 2636 2019 General
BASIC SCIENCE Immunophenotyping of a Stromal Vascular Fraction from Microfragmented Lipoaspirate Used in Osteoarthritis Cartilage Treatment and Its Lipoaspirate Counterpart HUDETZ, D., BORIC, I. et al., Genes 2019, 10, 474 2019 Cartilage
BASIC SCIENCE Micro-fragmented fat injection reduces sepsis induced acute inflammatory response in a mouse model BOUGLÉ, A., et al.  British Journal of Anaesthesia, 2018. 2018 Bacteria
BASIC SCIENCE A Nonenzymatic and Automated Closed-Cycle Process for the Isolation of Mesenchymal Stromal Cells in Drug Delivery Applications COCCE, V., et al. Stem Cells International, 2018 2018 Drug Delivery
BASIC SCIENCE Metabolomic changes in human adipose tissue derived products following non-enzymatic microfacturing GARCIA-CONTRERAS, M., et al. European review for medical and pharmacological sciences, 2018; 22(10):3249-3260. 2018 General
BASIC SCIENCE Effect of microfragmented adipose tissue on osteoarthritic synovial macrophage factors  PAOLELLA, F., et al. Journal of cellular physiology, 2018; 1-12, 2018 Synovium
BASIC SCIENCE Higher Pericyte Content and Secretory Activity of Microfragmented Human Adipose Tissue Compared to Enzymatically Derived Stromal Vascular Fraction  VEZZANI, B., et al. Stem cells translational medicine, 2018. 2018 Pericyte
GEN SURG Use of adipose tissue stem cells in chronic skin lesions: clinical experience MOFFA, F., et al. Italian Journal of Wound Care, 2018; 2(2):37-39. 2018 Skin
GEN SURG Micro-fragmented adipose tissue injection for the treatment of complex anal fistula: a pilot study accessing safety and feasibility NALDINI, G., et al. Techniques in coloproctology, 2018; 22(2):107-113. 2018 Fistula
GYN Menopause: new frontiers in the treatment of urogenital atrophy CASAROTTI, G.A., et al. European review for medical and pharmacological sciences, 2018; 22:567-574. 2018 Urogyn
ORTHO Micro-fragmented adipose tissue injection associated with arthroscopic procedures in patients with symptomatic knee osteoarthritis CATTANEO, G., et al. BMC musculoskeletal disorders, 2018; 19(1):176. 2018 Knee Adjunct
ORTHO Autologous microfractured and purified adipose tissue for arthroscopic management of osteochondral lesions of the talus D’AMBROSI, R., et al. JoVE (Journal of Visualized Experiments), 2018; 131:e56395-e56395. 2018 Foot/ankle
ORTHO Microfragmented adipose injections in the treatment of knee osteoarthritis MALANGA, G. A., BEMANIAN, S.  Journal of Clinical Orthopaedics & Trauma, 2018. 2018 Knee Standalone
ORTHO Safety and Efficacy of Percutaneous Injection of Lipogems Micro-Fractured Adipose Tissue for Osteoarthritic Knees PANCHAL, J., et al. The American Journal of Orthopedics, 2018. 2018 Knee Standalone
ORTHO Preliminary results of autologous adipose-derived stem cells
in early knee osteoarthritis: identification of a subpopulation
with greater response
PANNI, A. S., et al.  International orthopaedics, 2018, 1-7. 2018 Knee Adjunct
ORTHO Autologous micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis: an update at 3 year follow-up RUSSO, A., et al. Journal of Experimental Orthopaedics, 2018; 5:52. 2018 Knee Adjunct
ORTHO Refractory Shoulder Pain with Osteoarthritis, and Rotator Cuff Tear, Treated With Micro-Fragmented Adipose Tissue BILBOOL, N., et al. Orthop Spine Sports Med, 2018; 2(1):014 2018 Shoulder
VET Intra‐Articular Administration of Autologous Micro‐Fragmented Adipose Tissue in Dogs with Spontaneous Osteoarthritis: Safety, Feasibility, and Clinical Outcomes ZEIRA, O., et al. Stem cells translational medicine, 2018; 0(0):1–10. 2018 Canine
BASIC SCIENCE Cell melodies: when sound speaks to stem cells VENTURA, C., et al. CellR4 2017; 5 (2): e2331 2017 Signaling
ORTHO The Effect of Intra-articular Injection of Autologous Microfragmented Fat Tissue on Proteoglycan Synthesis in Patients with Knee Osteoarthritis HUDETZ, D., et al. Genes, 2017; 8(10):270. 2017 Knee Standalone
ORTHO Adipose-Derived Stem Cell Transplant Technique for Degenerative Joint Disease MOORMAN, T., et al. Arthroscopy Techniques, Vol 6, No 5 (October), 2017 2017 General Adjunct
ORTHO Adipose derived mesenchymal stem cells and arthroscopic surgery  MOORMAN, T., et al. Duke journal 2017 General Adjunct
ORTHO Autologous and micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis RUSSO, A., et al. Journal of Experimental Orthopaedics, 2017; 4:33. 2017 Knee Adjunct
ORTHO (Italiano) LIPO-AMIC: technical description and eighteen pilot patients report on AMIC® technique modified by adipose tissue mesenchymal cells augmentation SCIARRETTA, F., et al. Giornale Italiano di Ortopedia e Traumatologia 2017;43:156-162 2017 Knee Adjunct
ORTHO Non-Responding Knee Pain with Osteoarthritis, Meniscus and Ligament Tears Treated with Ultrasound Guided Autologous, Micro-Fragmented and Minimally Manipulated Adipose Tissue BILBOOL, N., et al. Open Journal of Regenerative Medicine, 2017; 6:17-26. 2017 Knee Standalone
ORTHO Arthroscopic treatment of chondral defects in the hip: AMIC, MACI, microfragmented adipose tissue transplantation (MATT) and other options E. JANNELLI and A. FONTANA: SICOT J 2017, 3, 43 2017 Hip
REVIEW Mesenchymal Stem Cells and Regenerative Medicine: How Lipogems Technology Make Them Easy, Safe and More Effective to Use TREMOLADA, C. MOJ Biology and Medicine 2017 2017  
BASIC SCIENCE Human lipoaspirate as autologous injectable active scaffold for one-step repair of cartilage defects BOSETTI, M., et al. Cell transplantation, 2016; 25(6):1043-1056. 2016 Cartilage
BASIC SCIENCE Angiogenic and anti-inflammatory properties of micro-fragmented fat tissue and its derived mesenchymal stromal cells CESERANI, V., et al. Vascular cell, 2016; 8:3. 2016 General
BASIC SCIENCE The Adipose Mesenchymal Stem Cell Secretome Inhibits Inflammatory Responses of Microglia: Evidence for an Involvement of Sphingosine-1-Phosphate Signalling MARFIA, G., et al. Stem Cells and Development, 2016 2016 Signaling
BASIC SCIENCE Lipogems product treatment increases the proliferation rate of human tendon stem cells without affecting their stemness and differentiation capability  RANDELLI, P., et al. Stem cells international, 2016. 2016 Tendon
GYN Autologous adipose tissue graft in the vulva in severe vulvar lichen sclerosus atrophicus: clinical case DE VITA, D., et al. Italian Journal of Gynaecology & Obstetrics, 2016; 28(5).  2016 Urogyn
GYN Microfractured and purified adipose tissue (Lipogems™ system) injections for treatment of atrophic vaginitis FANTASIA, J., et al. The Journal of Urology, 2016, 3.7:1073. 2016 Urogyn
ORTHO Injection of autologous micro-fragmented adipose tissue for the treatment of post-traumatic degenerative lesion of knee cartilage: a case report FRANCESCHINI, M., et al. CellR4, 2016; 4(1):e1768. 2016 Knee Standalone
ORTHO Low back pain treated with disc decompression and autologous micro-fragmented adipose tissue: a case report GROSSI, P., et al. CellR4, 2016; 1772:4. 2016 Spine
REVIEW Mesenchymal Stem Cells in Lipogems, a Reverse Story: from Clinical Practice to Basic Science TREMOLADA, RICORDI, CAPLAN, VENTURA. Mesenchymal Stem Cells: Methods and Protocols, Methods in Molecular Biology 2016  
REVIEW Adipose tissue and mesenchymal stem cells: state of the art and Lipogems® technology development  TREMOLADA, C., et al. Current stem cell reports, 2016; 2(3):304-312. 2016  
REVIEW Mesenchymal stem cells in lipogems, a reverse story: from clinical practice to basic science.” Mesenchymal Stem Cells. Humana Press, New York, NY, 2016. 109-122. TREMOLADA, C., et al. Mesenchymal Stem Cells. Humana Press, New York, NY, 2016. 109-122. 2016  
BASIC SCIENCE Characteristics and properties of mesenchymal stem cells derived from microfragmented adipose tissue  CARELLI, S., et al. Cell transplantation, 2015; 24(7):1233-1252. 2015 General
BASIC SCIENCE Differences in exosome content of human adipose tissue processed by non-enzymatic and enzymatic methods GARCÍA-CONTRERAS, M., et al. CellR4, 2015; 3(1):e1423. 2015 Exosomes
GEN SURG Intersphincteric anal lipofilling with micro-fragmented fat tissue for the treatment of faecal incontinence: preliminary results of three patients CESTARO, G., et al. Videosurgery and Other Miniinvasive Techniques, 2015; 10(2):337–341. 2015 Fecal Incontinence
GEN SURG Recovery of function in anal incontinence after micro-fragmented fat graft (Lipogems®) injection: two years follow up of the first 5 cases GIORI, A., et al. CellR4, 2015; 3(2):e1544. 2015 Fecal Incontinence
GEN SURG Microfractured lipoaspirate may help oral bone and soft tissue regeneration: a case report  BENZI, R., et al. CellR4, 2015; 3(3):e1583. 2015 Oral
GEN SURG Transnasal endoscopic microfractured fat injection in glottic insufficiency SAIBENE, A. M., et al. B-ENT, 2015; 11(3):229-34. 2015 Glottis
ORTHO Non-Responsive Knee Pain with Osteoarthritis and Concurrent Meniscal Disease Treated With Autologous Micro-Fragmented Adipose Tissue Under Continuous Ultrasound Guidance BILBOOL, N., et al. CellR4, 2015; 3(5):e1690. 2015 Knee Standalone
REVIEW Mesenchymal stem cells: potential for therapy and treatment of chronic non-healing skin wounds MARFIA, G., et al. Organogenesis 11.4 (2015): 183-206 2015  
REVIEW Enzymatic and non-enzymatic isolation systems for adipose tissue-derived cells: current state of the art  OBERBAUER, E., et al. Cell Regeneration 4.1 (2015): 7. 2015  
BASIC SCIENCE Lipogems, a New Modality of Fat Tissue Handling to Enhance Tissue Repair in Chronic Hind Limb Ischemia BIANCHI, F., VENTURA,, et al. CellR4, 2014 2014 Muscle
BASIC SCIENCE Human stem cell exposure to developmental stage zebrafish extracts: a novel strategy for tuning stemness and senescence patterning CANAIDER, S., et al. CellR4, 2014 2014 Senescence
BASIC SCIENCE Radioelectric Asymmetric Conveyed Fields and Human Adipose-Derived Stem Cells Obtained With a Nonenzymatic Method and Device: A Novel Approach to Multipotency MAIOLI, M., et al. Cell Transplantation, Vol. 23, pp. 1489–1500, 2014 2014 General
GEN SURG Micro Fractured and Purified Adipose Tissue Graft (Lipogems®) Can Improve the Orthognathic Surgery Outcomes Both Aesthetically and in Postoperative Healing RAFFAINI, M., et al. CellR4, 2014; 2(4):e1118. 2014 Aesthetics
BASIC SCIENCE A new non-enzymatic method and device to obtain a fat tissue derivative highly enriched in pericyte-like elements by mild mechanical forces from human lipoaspirates BIANCHI, F., et al. Cell transplantation, 2013; 22(11):2063-2077. 2013 General
ORTHO Outcomes after Micronized Fat Adipose Transfer for Glenohumeral Joint Arthritis and Rotator Cuff Pathology: a Case Series of 18 Shoulders Borg-Stein et al, Muscles, Ligaments and Tendons Journal 2020;10 (3):393-398  2002 Shoulder